


Her clothing was found submerged in the same tank. Lam's nude body was found more than two weeks after her disappearance, floating in a water tank on the hotel's roof. It also focuses on web sleuths, who became obsessed with the story after Los Angeles police released what many viewed as disturbing surveillance video of Lam in a hotel elevator, the last time she was known to have been seen.
ELIZA LAM TUBERCULOSIS SERIES
The series focuses on Lam's disappearance coupled with the seedy, sometimes violent history of the Cecil, which was located in L.A.'s Skid Row district, where she stayed briefly during a tourist trip to California. But the way it unfolded may have been just one exhibit of how the internet can take a tragedy with unusual circumstances and turn it into something that it isn't.Īlthough the 21-year-old college student from Vancouver, British Columbia, Canada, passed away in 2013, the case has maintained its staying power in the public imagination, as evidenced by a four-part Netflix documentary, "Crime Scene: The Vanishing at the Cecil Hotel," released in February 2021 - eight years after her passing. The Lam story, in the end, was the story of a young woman experiencing a mental health crisis who never received the help she desperately needed. But in the end, it's the " unsolved mystery" that was actually solved and not so mysterious. Future and adequately powered studies in a primary care setting should now specifically target patients with suspected TB who have advanced HIV infection.The Elisa Lam tragedy has for years been the subject of public fixation and numerous conspiracy theories. However, even in this group sensitivity was modest. smear-negative HIV-infected TB patients with a CD4 count <200 cells/mm(3), who would otherwise have required further investigation. These preliminary data indicate that in a high burden primary care setting the diagnostic usefulness of urine-LAM is limited, as a rule-in test, to a specific patient subgroup i.e. Sputum-LAM had good sensitivity (86%) but poor specificity (15%) likely due to test cross-reactivity with several mouth-residing organisms including actinomycetes and nocardia species. 25% of smear-negative but culture-positive HIV-infected patients with a CD4 <200 cells/mm(3) were positive for urine-LAM. Urine-LAM remained highly specific in all 3 subgroups (95%-100%). Urine-LAM positivity was associated with HIV positivity (p = 0.007) and test sensitivity, although low, was significantly higher in HIV-infected compared to uninfected patients (21% versus 6% p200 cells/mm(3) (37% versus 0% p = 0.003). Of 440 evaluable patients 120/387 (31%) were HIV-infected. tuberculosis was used as the reference standard for TB diagnosis. LAM was measured in sputum and urine samples obtained from 500 consecutively recruited ambulant patients, with suspected TB, from 2 primary care clinics in South Africa. The utility of LAM in sputum samples has, hitherto, not been evaluated. Recent studies indicate that a lipoarabinomannan (LAM) assay (Clearview-TB(R)-ELISA) may have some utility for the diagnosis of TB in HIV-infected patients however, the precise subgroup that may benefit from this technology requires clarification. The accurate diagnosis of TB in HIV-infected patients, particularly with advanced immunosuppression, is difficult.
